Nrf2/HO-1 pathway activation by manganese is associated with reactive oxygen species and ubiquitin-proteasome pathway, not MAPKs signaling. [electronic resource]
Producer: 20120222Description: 690-7 p. digitalISSN:- 1099-1263
- Animals
- Antioxidants -- metabolism
- Heme Oxygenase-1 -- genetics
- Manganese -- toxicity
- Mitogen-Activated Protein Kinases -- genetics
- NF-E2-Related Factor 2 -- genetics
- Oxidative Stress -- drug effects
- PC12 Cells
- Proteasome Endopeptidase Complex -- metabolism
- Rats
- Reactive Oxygen Species -- metabolism
- Signal Transduction -- drug effects
- Ubiquitin -- genetics
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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