TGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease. [electronic resource]
Producer: 20110629Description: e110 p. digitalISSN:- 2041-4889
- Alzheimer Disease -- genetics
- Amyloid beta-Peptides -- metabolism
- Amyloid beta-Protein Precursor -- genetics
- Animals
- Apoptosis
- Apoptosis Regulatory Proteins -- genetics
- COS Cells
- Chlorocebus aethiops
- Hippocampus -- metabolism
- Humans
- Mice
- Mice, Transgenic
- Nuclear Proteins -- genetics
- Phosphorylation
- Plaque, Amyloid -- etiology
- Polymerization
- Signal Transduction
- Smad4 Protein -- analysis
- Transforming Growth Factor beta -- metabolism
- Two-Hybrid System Techniques
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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