Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway. [electronic resource]
Producer: 20110415Description: 678-92 p. digitalISSN:- 1460-2156
- 2',3'-Cyclic-Nucleotide Phosphodiesterases -- metabolism
- Aldehyde Reductase -- metabolism
- Animals
- Antigens, Differentiation -- metabolism
- Antioxidants -- metabolism
- Astrocytes -- drug effects
- Axons -- metabolism
- CD3 Complex -- metabolism
- Cell Proliferation -- drug effects
- Cells, Cultured
- Chromatography, High Pressure Liquid -- methods
- Cytokines -- metabolism
- Disease Models, Animal
- Embryo, Mammalian
- Encephalomyelitis, Autoimmune, Experimental -- etiology
- Female
- Fumarates -- pharmacology
- Gene Expression Regulation -- drug effects
- Glycoproteins -- adverse effects
- Green Fluorescent Proteins -- genetics
- Humans
- Hydrogen Peroxide -- pharmacology
- Mass Spectrometry
- Mice
- Mice, Inbred C57BL
- Motor Neurons -- cytology
- Multiple Sclerosis -- metabolism
- Myelin Proteins -- metabolism
- Myelin-Oligodendrocyte Glycoprotein
- NAD(P)H Dehydrogenase (Quinone) -- metabolism
- NF-E2-Related Factor 2 -- metabolism
- Neuroprotective Agents -- pharmacology
- Nogo Proteins
- Oxidative Stress -- drug effects
- Peptide Fragments -- adverse effects
- RNA, Small Interfering -- pharmacology
- Signal Transduction -- drug effects
- Sleep -- physiology
- Spinal Cord -- cytology
- Statistics, Nonparametric
- Tandem Mass Spectrometry -- methods
- Time Factors
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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