9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response. [electronic resource]
Producer: 20110228Description: 264-8 p. digitalISSN:- 1476-4687
- Alleles
- Cell Line
- Chromatin -- drug effects
- Chromosomes, Human, Pair 9 -- genetics
- Conserved Sequence -- genetics
- Coronary Artery Disease -- genetics
- Cyclin-Dependent Kinase Inhibitor p15 -- genetics
- Diabetes Mellitus, Type 2 -- genetics
- Endothelial Cells -- drug effects
- Enhancer Elements, Genetic -- genetics
- Gene Expression Regulation -- drug effects
- Gene Knockdown Techniques
- Genetic Predisposition to Disease -- genetics
- Genetic Variation
- Genome-Wide Association Study
- Haplotypes -- genetics
- HeLa Cells
- Humans
- Interferon-alpha -- genetics
- Interferon-gamma -- pharmacology
- Linkage Disequilibrium
- Male
- Polymorphism, Single Nucleotide -- genetics
- Protein Binding -- drug effects
- Purine-Nucleoside Phosphorylase -- genetics
- STAT1 Transcription Factor -- biosynthesis
- Signal Transduction -- drug effects
- White People -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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