Adrenal beta-arrestin 1 inhibition in vivo attenuates post-myocardial infarction progression to heart failure and adverse remodeling via reduction of circulating aldosterone levels. [electronic resource]
Producer: 20110214Description: 356-65 p. digitalISSN:- 1558-3597
- Adrenal Glands -- drug effects
- Aldosterone -- biosynthesis
- Animals
- Arrestins -- antagonists & inhibitors
- Cell Line
- Disease Progression
- Gene Transfer Techniques
- Heart Failure -- blood
- Humans
- Losartan -- pharmacology
- Myocardial Infarction -- blood
- Random Allocation
- Rats
- Receptors, G-Protein-Coupled -- antagonists & inhibitors
- Ventricular Remodeling -- drug effects
- beta-Arrestin 1
- beta-Arrestins
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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