Hypomorphic Rag mutations can cause destructive midline granulomatous disease. [electronic resource]
Producer: 20100930Description: 1263-71 p. digitalISSN:- 1528-0020
- Adolescent
- Animals
- Cells, Cultured
- Forkhead Transcription Factors
- Gene Rearrangement
- Genes, Immunoglobulin
- Granulomatous Disease, Chronic -- etiology
- Homeodomain Proteins -- genetics
- Humans
- Immunoglobulin G -- immunology
- Immunophenotyping
- Lymphocytes -- immunology
- Male
- Mice
- Mutation, Missense -- genetics
- Recombinases -- metabolism
- Severe Combined Immunodeficiency -- etiology
- T-Lymphocytes, Regulatory -- immunology
- Thymectomy
- Transcription Factors
- Transgenes -- physiology
- AIRE Protein
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Publication Type: Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
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