Functionalized aurones as inducers of NAD(P)H:quinone oxidoreductase 1 that activate AhR/XRE and Nrf2/ARE signaling pathways: synthesis, evaluation and SAR. [electronic resource]
Producer: 20100817Description: 2957-71 p. digitalISSN:- 1768-3254
- Animals
- Antioxidants -- metabolism
- Benzofurans -- chemical synthesis
- Cell Line, Tumor
- Cytochrome P-450 CYP1A1 -- metabolism
- Enzyme Induction -- drug effects
- Mice
- Mutation
- NF-E2-Related Factor 2 -- metabolism
- Quantitative Structure-Activity Relationship
- Quinone Reductases -- biosynthesis
- Receptors, Aryl Hydrocarbon -- metabolism
- Response Elements
- Signal Transduction -- drug effects
- Xenobiotics -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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