First evidence that the antimalarial drug artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases. [electronic resource]
Producer: 20100824Description: 1475-85 p. digitalISSN:- 1097-0215
- Animals
- Antimalarials -- pharmacology
- Artemisinins -- pharmacology
- Artesunate
- Carcinoma, Non-Small-Cell Lung -- enzymology
- Cell Proliferation -- drug effects
- Chick Embryo
- Enzyme-Linked Immunosorbent Assay
- Gene Expression Profiling
- Humans
- Lung Neoplasms -- enzymology
- Matrix Metalloproteinases -- genetics
- Neoplasm Invasiveness -- prevention & control
- Neoplasm Metastasis -- prevention & control
- Polymerase Chain Reaction
- RNA, Messenger -- genetics
- Urokinase-Type Plasminogen Activator -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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