Securinine induces p73-dependent apoptosis preferentially in p53-deficient colon cancer cells. [electronic resource]
Producer: 20100721Description: 2126-34 p. digitalISSN:- 1530-6860
- Apoptosis -- drug effects
- Azepines -- pharmacology
- Blotting, Western
- Caspase Inhibitors
- Caspases -- metabolism
- Cell Adhesion -- drug effects
- Cell Cycle -- drug effects
- Cell Proliferation -- drug effects
- Colonic Neoplasms -- drug therapy
- DNA Damage -- drug effects
- DNA-Binding Proteins -- genetics
- Heterocyclic Compounds, 4 or More Rings -- pharmacology
- Heterocyclic Compounds, Bridged-Ring
- Humans
- Lactones -- pharmacology
- Nuclear Proteins -- genetics
- Piperidines -- pharmacology
- RNA, Messenger -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Tumor Cells, Cultured
- Tumor Protein p73
- Tumor Suppressor Protein p53 -- genetics
- Tumor Suppressor Proteins -- genetics
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Publication Type: Journal Article
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