Design and synthesis of novel diaminoquinazolines with in vivo efficacy for beta-catenin/T-cell transcriptional factor 4 pathway inhibition. [electronic resource]
Producer: 20100302Description: 897-910 p. digitalISSN:- 1520-4804
- Animals
- Basic Helix-Loop-Helix Leucine Zipper Transcription Factors -- drug effects
- Cell Line, Tumor
- Colorectal Neoplasms -- drug therapy
- Drug Design
- Humans
- Mice
- Quinazolines -- chemical synthesis
- Structure-Activity Relationship
- TCF Transcription Factors -- drug effects
- Transcription Factor 4
- Transcription Factors -- drug effects
- Treatment Outcome
- Xenograft Model Antitumor Assays
- beta Catenin -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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