Extracellular signal-regulated kinase 1/2 and c-Jun NH2-terminal kinase, through nuclear factor-kappaB and activator protein-1, contribute to caerulein-induced expression of substance P and neurokinin-1 receptors in pancreatic acinar cells. [electronic resource]
Producer: 20100413Description: 940-8 p. digitalISSN:- 1521-0103
- Acute Disease
- Animals
- Ceruletide -- pharmacology
- JNK Mitogen-Activated Protein Kinases -- antagonists & inhibitors
- Male
- Mice
- Mitogen-Activated Protein Kinase 1 -- antagonists & inhibitors
- Mitogen-Activated Protein Kinase 3 -- antagonists & inhibitors
- NF-kappa B -- physiology
- Pancreas -- cytology
- Pancreatitis -- metabolism
- Phosphorylation
- Protein Precursors -- biosynthesis
- Receptor, Cholecystokinin A -- physiology
- Receptors, Neurokinin-1 -- biosynthesis
- Signal Transduction
- Substance P -- biosynthesis
- Tachykinins -- biosynthesis
- Transcription Factor AP-1 -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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