Lysosomal destabilization and cathepsin B contributes for cytochrome c release and caspase activation in embelin-induced apoptosis. [electronic resource]
Producer: 20100512Description: 324-36 p. digitalISSN:- 1098-2744
- Apoptosis -- drug effects
- Benzoquinones -- chemistry
- Caspases -- genetics
- Cathepsin B -- metabolism
- Cell Line, Tumor
- Cyclin-Dependent Kinase Inhibitor p21 -- genetics
- Cytochromes c -- metabolism
- Dose-Response Relationship, Drug
- Enzyme Activation
- HCT116 Cells
- Humans
- Lysosomes -- metabolism
- Membrane Potential, Mitochondrial -- drug effects
- Mitochondria -- metabolism
- Tumor Suppressor Protein p53 -- metabolism
- bcl-2-Associated X Protein -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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