Inhibition of the hedgehog pathway in advanced basal-cell carcinoma. [electronic resource]
Producer: 20090923Description: 1164-72 p. digitalISSN:- 1533-4406
- Adult
- Aged
- Aged, 80 and over
- Anilides
- Antineoplastic Agents -- administration & dosage
- Benzimidazoles -- administration & dosage
- Carcinoma, Basal Cell -- drug therapy
- Dose-Response Relationship, Drug
- Female
- Gene Expression
- Hedgehog Proteins -- antagonists & inhibitors
- Humans
- Male
- Middle Aged
- Mutation
- Patched Receptors
- Patched-1 Receptor
- Polymerase Chain Reaction
- Pyridines
- RNA, Messenger -- metabolism
- Receptors, Cell Surface -- genetics
- Sequence Analysis, DNA
- Signal Transduction -- drug effects
- Skin Neoplasms -- drug therapy
- Transcription Factors -- genetics
- Zinc Finger Protein GLI1
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Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
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