The Gli3 transcription factor expressed in the thymus stroma controls thymocyte negative selection via Hedgehog-dependent and -independent mechanisms. [electronic resource]
Producer: 20090918Description: 3023-32 p. digitalISSN:- 1550-6606
- Animals
- Autoimmune Diseases -- immunology
- Cell Differentiation -- genetics
- Female
- Gene Expression Regulation, Developmental -- immunology
- Growth Inhibitors -- biosynthesis
- Hedgehog Proteins -- physiology
- Kruppel-Like Transcription Factors -- biosynthesis
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mice, Transgenic
- Nerve Tissue Proteins -- biosynthesis
- Organ Culture Techniques
- Receptors, Antigen, T-Cell -- biosynthesis
- Stromal Cells -- immunology
- Thymus Gland -- cytology
- Zinc Finger Protein Gli3
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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