Evaluation of side effects through selective ablation of the mu opioid receptor expressing descending nociceptive facilitatory neurons in the rostral ventromedial medulla with dermorphin-saporin. [electronic resource]
Producer: 20100309Description: 1096-106 p. digitalISSN:- 1872-9711
- Analgesics, Opioid -- toxicity
- Animals
- CD11b Antigen -- metabolism
- Drinking -- drug effects
- Eating -- drug effects
- Echocardiography -- methods
- Enzyme-Linked Immunosorbent Assay -- methods
- Gene Expression Regulation -- drug effects
- Glial Fibrillary Acidic Protein -- metabolism
- Hyperalgesia -- mortality
- Immunotoxins -- toxicity
- Interleukin-1beta -- metabolism
- Male
- Medulla Oblongata -- cytology
- Microinjections
- Motor Activity -- drug effects
- Neurons -- drug effects
- Opioid Peptides -- toxicity
- Pain Measurement -- methods
- Pain Threshold -- drug effects
- Rats
- Rats, Wistar
- Receptors, Opioid, mu -- genetics
- Ribosome Inactivating Proteins, Type 1 -- toxicity
- Saporins
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article
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