A traditional medicinal herb Paeonia suffruticosa and its active constituent 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose have potent anti-aggregation effects on Alzheimer's amyloid beta proteins in vitro and in vivo. [electronic resource]
Producer: 20090717Description: 1648-57 p. digitalISSN:- 1471-4159
- Alzheimer Disease -- drug therapy
- Amyloid beta-Peptides -- metabolism
- Amyloid beta-Protein Precursor -- genetics
- Animals
- Avoidance Learning -- drug effects
- Behavior, Animal -- drug effects
- Cell Line, Transformed
- Cell Survival -- drug effects
- Chromatography, High Pressure Liquid -- methods
- Disease Models, Animal
- Enzyme-Linked Immunosorbent Assay
- Hydrolyzable Tannins -- pharmacology
- Memory -- drug effects
- Mice
- Mice, Transgenic
- Models, Molecular
- Paeonia -- chemistry
- Peptide Fragments -- metabolism
- Phytotherapy -- methods
- Plant Extracts -- pharmacology
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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