The integrin alpha2beta1 agonist, aggretin, promotes proliferation and migration of VSMC through NF-kB translocation and PDGF production. [electronic resource]
Producer: 20090615Description: 846-56 p. digitalISSN:- 1476-5381
- Animals
- Becaplermin
- Cell Movement
- Cell Proliferation
- Cells, Cultured
- Enzyme Activation
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Humans
- Integrin alpha2beta1 -- agonists
- Lectins, C-Type
- Muscle, Smooth, Vascular -- cytology
- Myocytes, Smooth Muscle -- cytology
- NF-kappa B -- metabolism
- Phosphorylation
- Platelet-Derived Growth Factor -- biosynthesis
- Protein Transport
- Proto-Oncogene Proteins c-sis
- Rats
- Receptor, Platelet-Derived Growth Factor beta -- agonists
- Signal Transduction
- Type C Phospholipases -- physiology
- Viper Venoms -- pharmacology
- src-Family Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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