Insulin activates the PI3K-Akt survival pathway in vulnerable neurons following global brain ischemia. [electronic resource]
Producer: 20100202Description: 947-58 p. digitalISSN:- 1743-1328
- Animals
- Apoptosis Regulatory Proteins -- drug effects
- Bcl-2-Like Protein 11
- Brain Ischemia -- drug therapy
- CA1 Region, Hippocampal -- drug effects
- Cell Survival -- drug effects
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Forkhead Box Protein O3
- Forkhead Transcription Factors -- drug effects
- Insulin -- metabolism
- Male
- Membrane Proteins -- drug effects
- Memory Disorders -- drug therapy
- Neurons -- drug effects
- Neuroprotective Agents -- metabolism
- Phosphatidylinositol 3-Kinases -- drug effects
- Phosphorylation -- drug effects
- Proto-Oncogene Proteins -- drug effects
- Proto-Oncogene Proteins c-akt -- drug effects
- Rats
- Rats, Long-Evans
- Reperfusion Injury -- drug therapy
- Signal Transduction -- drug effects
- bcl-Associated Death Protein -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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