CS1 promotes multiple myeloma cell adhesion, clonogenic growth, and tumorigenicity via c-maf-mediated interactions with bone marrow stromal cells. [electronic resource]
Producer: 20090602Description: 4309-18 p. digitalISSN:- 1528-0020
- Animals
- Antigens, Surface -- chemistry
- Biomarkers, Tumor -- genetics
- Bone Marrow -- metabolism
- Cell Adhesion -- physiology
- Cell Membrane
- Cell Proliferation
- Cell Survival
- Colony-Forming Units Assay
- Culture Media, Serum-Free -- pharmacology
- Enzyme-Linked Immunosorbent Assay
- Flow Cytometry
- Gene Expression Profiling
- Humans
- Immunoblotting
- Lentivirus -- genetics
- Membrane Proteins
- Mice
- Mice, SCID
- Microfilament Proteins
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Multiple Myeloma -- metabolism
- Oligonucleotide Array Sequence Analysis
- Phosphorylation
- Proto-Oncogene Proteins c-akt -- metabolism
- Proto-Oncogene Proteins c-maf -- genetics
- RNA, Small Interfering -- pharmacology
- STAT3 Transcription Factor -- metabolism
- Stromal Cells -- metabolism
- Transcriptional Activation
- Transfection
- Tumor Cells, Cultured
- Vascular Endothelial Growth Factor A -- genetics
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Retracted Publication
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