Anti-gout agent allopurinol exerts cytotoxicity to human hormone-refractory prostate cancer cells in combination with tumor necrosis factor-related apoptosis-inducing ligand. [electronic resource]
Producer: 20090202Description: 1852-60 p. digitalISSN:- 1541-7786
- Allopurinol -- pharmacology
- Antimetabolites -- pharmacology
- Apoptosis -- drug effects
- Cell Line, Tumor
- Drug Resistance, Neoplasm
- Drug Therapy, Combination
- Endoplasmic Reticulum -- metabolism
- Flow Cytometry
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Male
- Promoter Regions, Genetic -- physiology
- Prostatic Neoplasms -- drug therapy
- RNA, Small Interfering
- Receptors, TNF-Related Apoptosis-Inducing Ligand -- genetics
- Response Elements
- TNF-Related Apoptosis-Inducing Ligand -- pharmacology
- Transcription Factor CHOP -- genetics
- Up-Regulation -- drug effects
- Xanthine Oxidase -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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