Ca(2+)-dependent protein kinase C isoforms are critical to estradiol 17beta-D-glucuronide-induced cholestasis in the rat. [electronic resource]
Producer: 20090112Description: 1885-95 p. digitalISSN:- 1527-3350
- ATP Binding Cassette Transporter, Subfamily B, Member 11
- ATP-Binding Cassette Transporters -- metabolism
- Animals
- Calcium -- metabolism
- Carbazoles -- pharmacology
- Cells, Cultured
- Cholestasis -- chemically induced
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Enzyme Inhibitors -- pharmacology
- Estradiol -- adverse effects
- Female
- Hepatocytes -- drug effects
- Liver -- drug effects
- Protein Kinase C-alpha -- antagonists & inhibitors
- Protein Kinase C-epsilon -- antagonists & inhibitors
- Rats
- Rats, Sprague-Dawley
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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