Tumor necrosis factor alpha activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells. [electronic resource]
Producer: 20090223Description: 1642-52 p. digitalISSN:- 0891-5849
- Adaptor Proteins, Signal Transducing
- Adaptor Proteins, Vesicular Transport -- genetics
- Binding Sites
- Blotting, Northern
- Cells, Cultured
- Colon -- metabolism
- Electrophoretic Mobility Shift Assay
- Gene Expression Regulation, Enzymologic
- Humans
- Immunoblotting
- JNK Mitogen-Activated Protein Kinases -- metabolism
- Luciferases -- metabolism
- Phosphorylation
- Promoter Regions, Genetic
- Protein Binding
- Protein Isoforms
- Proto-Oncogene Proteins c-fos -- metabolism
- RNA, Messenger -- genetics
- Response Elements
- Reverse Transcriptase Polymerase Chain Reaction
- Subcellular Fractions
- Superoxides -- metabolism
- Transcription Factor AP-1 -- metabolism
- Transcription, Genetic
- Transfection
- Tumor Necrosis Factor-alpha -- pharmacology
- Up-Regulation
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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