Dual targeting of HSC70 and HSP72 inhibits HSP90 function and induces tumor-specific apoptosis. [electronic resource]
Producer: 20081015Description: 250-62 p. digitalISSN:- 1878-3686
- Apoptosis -- drug effects
- Benzoquinones -- pharmacology
- Boronic Acids -- pharmacology
- Bortezomib
- Cell Cycle -- drug effects
- Cell Line
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cyclin-Dependent Kinase 4 -- metabolism
- HCT116 Cells
- HSC70 Heat-Shock Proteins -- genetics
- HSP70 Heat-Shock Proteins -- metabolism
- HSP72 Heat-Shock Proteins -- genetics
- HSP90 Heat-Shock Proteins -- antagonists & inhibitors
- Humans
- Kinetics
- Lactams, Macrocyclic -- pharmacology
- Neoplasms -- genetics
- Poly(ADP-ribose) Polymerases -- metabolism
- Protease Inhibitors -- pharmacology
- Proteasome Endopeptidase Complex -- metabolism
- Proteasome Inhibitors
- Protein Isoforms -- genetics
- Proto-Oncogene Proteins c-raf -- metabolism
- Pyrazines -- pharmacology
- RNA, Small Interfering -- genetics
- Transfection
- Ubiquitination
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.