Conformationally constrained analogues of diacylglycerol. 30. An investigation of diacylglycerol-lactones containing heteroaryl groups reveals compounds with high selectivity for Ras guanyl nucleotide-releasing proteins. [electronic resource]
Producer: 20081024Description: 5371-86 p. digitalISSN:- 1520-4804
- Cell Membrane Permeability
- Diglycerides -- chemistry
- Guanine Nucleotide Exchange Factors -- metabolism
- Heterocyclic Compounds
- Humans
- Hydrophobic and Hydrophilic Interactions
- Lactones -- chemistry
- Molecular Conformation
- Protein Binding
- Protein Kinase C-alpha -- metabolism
- ras Guanine Nucleotide Exchange Factors
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Publication Type: Journal Article; Research Support, N.I.H., Intramural
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