Aging-resistant organophosphate bioscavenger based on polyethylene glycol-conjugated F338A human acetylcholinesterase. [electronic resource]
Producer: 20080918Description: 755-63 p. digitalISSN:- 1521-0111
- Acetylcholinesterase -- pharmacokinetics
- Alanine -- genetics
- Amino Acid Substitution
- Animals
- Binding Sites
- Cell Line
- Cholinesterase Inhibitors -- pharmacology
- Enzyme Activation -- drug effects
- Humans
- Hydrolysis -- drug effects
- Kinetics
- Male
- Mice
- Mice, Inbred ICR
- Organophosphorus Compounds -- metabolism
- Phenylalanine -- genetics
- Phosphorylation -- drug effects
- Polyethylene Glycols -- pharmacokinetics
- Soman -- toxicity
- Survival Analysis
- Time Factors
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
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