Impact of MDR1 and CYP3A5 on the oral clearance of tacrolimus and tacrolimus-related renal dysfunction in adult living-donor liver transplant patients. [electronic resource]
Producer: 20080709Description: 413-23 p. digitalISSN:- 1744-6872
- ATP Binding Cassette Transporter, Subfamily B
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- genetics
- Administration, Oral
- Adult
- Aged
- Cytochrome P-450 CYP3A -- genetics
- Drug Resistance -- genetics
- Enterocytes -- metabolism
- Female
- Genotype
- Graft Rejection -- genetics
- Humans
- Immunosuppressive Agents -- administration & dosage
- Kidney -- metabolism
- Liver Transplantation -- physiology
- Living Donors
- Male
- Metabolic Clearance Rate
- Middle Aged
- Pharmacogenetics
- Renal Insufficiency -- chemically induced
- Tacrolimus -- administration & dosage
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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