Histone deacetylase inhibitors exert time-dependent effects on nuclear factor-kappaB but consistently suppress the expression of proinflammatory genes in human myometrial cells. [electronic resource]
Producer: 20080725Description: 109-21 p. digitalISSN:- 1521-0111
- Biopsy
- Cells, Cultured
- Cesarean Section
- Dose-Response Relationship, Drug
- Enzyme Inhibitors -- pharmacology
- Female
- Gene Expression Regulation -- drug effects
- Genes, Reporter
- Histone Deacetylase Inhibitors
- Histone Deacetylases -- metabolism
- Humans
- Hydroxamic Acids -- pharmacology
- I-kappa B Kinase -- analysis
- Kinetics
- Luciferases, Firefly -- metabolism
- Myometrium -- cytology
- NF-kappa B -- genetics
- Pregnancy
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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