Constitutive production of NF-kappaB2 p52 is not tumorigenic but predisposes mice to inflammatory autoimmune disease by repressing Bim expression. [electronic resource]
Producer: 20080610Description: 10698-706 p. digitalISSN:- 0021-9258
- Animals
- Apoptosis Regulatory Proteins -- metabolism
- Autoantibodies -- chemistry
- Bcl-2-Like Protein 11
- Gene Expression Regulation
- Genetic Predisposition to Disease
- Humans
- Inflammation
- Lymphocytes -- metabolism
- Membrane Proteins -- metabolism
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Mutation
- NF-kappa B p52 Subunit -- biosynthesis
- Proto-Oncogene Proteins -- metabolism
- Signal Transduction
- Spleen -- cytology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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