Glycodelin A triggers mitochondrial stress and apoptosis in T cells by a mechanism distinct and independent of TCR signaling. [electronic resource]
Producer: 20080605Description: 2391-400 p. digitalISSN:- 0161-5890
- Apoptosis -- drug effects
- Calcium -- pharmacology
- Caspase 2 -- metabolism
- Ceramides -- pharmacology
- Enzyme Activation -- drug effects
- Glycodelin
- Glycoproteins -- pharmacology
- Humans
- Ionomycin -- pharmacology
- Jurkat Cells
- Leukocyte Common Antigens -- immunology
- Lymphocyte Activation -- drug effects
- Matrix Metalloproteinases -- metabolism
- Mitochondria -- drug effects
- Mitogen-Activated Protein Kinase 8 -- metabolism
- Pregnancy Proteins -- pharmacology
- Reactive Oxygen Species -- metabolism
- Receptors, Antigen, T-Cell -- immunology
- Signal Transduction -- drug effects
- T-Lymphocytes -- cytology
- Tetradecanoylphorbol Acetate -- pharmacology
- fas Receptor -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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