Ectopic decorin expression up-regulates VEGF expression in mouse cerebral endothelial cells via activation of the transcription factors Sp1, HIF1alpha, and Stat3. [electronic resource]
Producer: 20080506Description: 324-37 p. digitalISSN:- 1471-4159
- Analysis of Variance
- Animals
- Cerebral Cortex -- cytology
- Chromatin Immunoprecipitation -- methods
- Decorin
- Electrophoretic Mobility Shift Assay -- methods
- Endothelial Cells -- metabolism
- Enzyme Activation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Extracellular Matrix Proteins -- metabolism
- Hypoxia-Inducible Factor 1, alpha Subunit -- genetics
- Mice
- Models, Biological
- Neovascularization, Physiologic -- drug effects
- Proteoglycans -- metabolism
- RNA, Small Interfering -- pharmacology
- STAT3 Transcription Factor -- genetics
- Sp1 Transcription Factor -- genetics
- Transcription Factors -- genetics
- Transfection -- methods
- Up-Regulation -- drug effects
- Vascular Endothelial Growth Factor A -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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