Glial cell-derived neurotrophic factor protects against proteasome inhibition-induced dopamine neuron degeneration by suppression of endoplasmic reticulum stress and caspase-3 activation. [electronic resource]
Producer: 20071101Description: 943-50 p. digitalISSN:- 1079-5006
- Acetylcysteine -- analogs & derivatives
- Animals
- Apoptosis -- drug effects
- Caspase 3 -- metabolism
- Cells, Cultured
- Dopamine -- metabolism
- Endoplasmic Reticulum -- drug effects
- Enzyme Activation -- drug effects
- Glial Cell Line-Derived Neurotrophic Factor -- pharmacology
- Humans
- Inclusion Bodies -- drug effects
- Nerve Degeneration -- metabolism
- Neurons -- drug effects
- Parkinson Disease -- metabolism
- Proteasome Inhibitors
- Rats
- Recombinant Proteins -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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