The oncoprotein NPM-ALK of anaplastic large-cell lymphoma induces JUNB transcription via ERK1/2 and JunB translation via mTOR signaling. [electronic resource]
Producer: 20071213Description: 3374-83 p. digitalISSN:- 0006-4971
- Anaplastic Lymphoma Kinase
- Catalytic Domain -- physiology
- Gene Expression Profiling
- Gene Expression Regulation, Neoplastic
- Humans
- Lymphoma, Large-Cell, Anaplastic -- genetics
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Oligonucleotide Array Sequence Analysis
- Protein Binding
- Protein Biosynthesis
- Protein Kinases -- physiology
- Protein-Tyrosine Kinases -- chemistry
- Proto-Oncogene Proteins c-jun -- genetics
- RNA, Messenger -- metabolism
- Receptor Protein-Tyrosine Kinases
- Signal Transduction -- physiology
- TOR Serine-Threonine Kinases
- Transcription Factor AP-1 -- genetics
- Transcriptional Activation
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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