Attenuated expression of episodic growth hormone-induced CYP2C11 in female rats associated with suboptimal activation of the Jak2/Stat5B and other modulating signaling pathways. [electronic resource]
Producer: 20080117Description: 2102-10 p. digitalISSN:- 0090-9556
- Animals
- Aryl Hydrocarbon Hydroxylases -- genetics
- Blotting, Western
- Cytochrome P-450 CYP3A
- Cytochrome P450 Family 2
- Female
- Gene Expression -- drug effects
- Growth Hormone -- administration & dosage
- Hypophysectomy
- I-kappa B Proteins -- metabolism
- Janus Kinase 2 -- metabolism
- Liver -- cytology
- Male
- Membrane Proteins -- genetics
- Mitogen-Activated Protein Kinases -- metabolism
- NF-KappaB Inhibitor alpha
- Phosphorylation -- drug effects
- Promoter Regions, Genetic -- genetics
- Protein Binding
- Rats
- Rats, Sprague-Dawley
- Reverse Transcriptase Polymerase Chain Reaction
- STAT5 Transcription Factor -- metabolism
- Sex Factors
- Signal Transduction -- drug effects
- Steroid 16-alpha-Hydroxylase -- genetics
- Steroid Hydroxylases -- genetics
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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