Selective sigma-2 ligands preferentially bind to pancreatic adenocarcinomas: applications in diagnostic imaging and therapy. [electronic resource]
Producer: 20071015Description: 48 p. digitalISSN:- 1476-4598
- Adenocarcinoma -- drug therapy
- Animals
- Antineoplastic Agents -- metabolism
- Apoptosis -- drug effects
- Azabicyclo Compounds -- metabolism
- Binding, Competitive
- Brain -- cytology
- Carbamates -- metabolism
- Caspase 3 -- metabolism
- Cell Line, Tumor
- Cell Survival -- drug effects
- Dose-Response Relationship, Drug
- Female
- Humans
- Kidney -- cytology
- Ligands
- Lung -- cytology
- Mice
- Mice, Inbred C57BL
- Neoplasms, Experimental -- drug therapy
- Pancreatic Neoplasms -- drug therapy
- Positron-Emission Tomography
- Radioligand Assay
- Receptors, sigma -- agonists
- Signal Transduction -- drug effects
- Survival Analysis
- Tritium
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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