Yeast cells lacking the CIT1-encoded mitochondrial citrate synthase are hypersusceptible to heat- or aging-induced apoptosis. [electronic resource]
Producer: 20071109Description: 3556-67 p. digitalISSN:- 1059-1524
- Apoptosis -- drug effects
- Biological Transport -- drug effects
- Biomarkers -- metabolism
- Caspase Inhibitors
- Caspases
- Citrate (si)-Synthase -- deficiency
- DNA Fragmentation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Gene Deletion
- Glutamates -- metabolism
- Glutathione -- metabolism
- Heat-Shock Response -- drug effects
- Hot Temperature
- Mitochondria -- drug effects
- Phenotype
- Phosphatidylserines -- metabolism
- Reactive Oxygen Species -- metabolism
- Saccharomyces cerevisiae -- cytology
- Saccharomyces cerevisiae Proteins -- antagonists & inhibitors
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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