Biotechnological synthesis of drug metabolites using human cytochrome P450 2D6 heterologously expressed in fission yeast exemplified for the designer drug metabolite 4'-hydroxymethyl-alpha-pyrrolidinobutyrophenone. [electronic resource]
Producer: 20070921Description: 511-20 p. digitalISSN:- 0006-2952
- Biotechnology
- Butyrophenones -- metabolism
- Chromatography, High Pressure Liquid
- Cytochrome P-450 CYP2D6 -- genetics
- Gas Chromatography-Mass Spectrometry
- Humans
- Magnetic Resonance Spectroscopy
- Pyrrolidines -- metabolism
- Recombinant Proteins -- genetics
- Schizosaccharomyces -- genetics
- Spectrophotometry, Ultraviolet
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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