Mutation in the key enzyme of sialic acid biosynthesis causes severe glomerular proteinuria and is rescued by N-acetylmannosamine. [electronic resource]
Producer: 20070710Description: 1585-94 p. digitalISSN:- 0021-9738
- Animals
- Base Sequence
- DNA Primers -- genetics
- Disease Models, Animal
- Female
- Hexosamines -- therapeutic use
- Humans
- Kidney Diseases -- drug therapy
- Kidney Glomerulus -- metabolism
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Mice, Transgenic
- Microscopy, Electron
- Models, Biological
- Multienzyme Complexes -- genetics
- N-Acetylneuraminic Acid -- biosynthesis
- Pregnancy
- Proteinuria -- drug therapy
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Intramural
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