Interferon-gamma sensitizes resistant Ewing's sarcoma cells to tumor necrosis factor apoptosis-inducing ligand-induced apoptosis by up-regulation of caspase-8 without altering chemosensitivity. [electronic resource]
Producer: 20070717Description: 1917-30 p. digitalISSN:- 0002-9440
- Adolescent
- Adult
- Animals
- Antibiotics, Antineoplastic -- therapeutic use
- Apoptosis -- physiology
- Bone Neoplasms -- drug therapy
- Caspase 8 -- genetics
- Cell Line
- Child
- Doxorubicin -- therapeutic use
- Drug Resistance, Neoplasm
- Embryonic Stem Cells -- cytology
- Female
- Humans
- Interferon-gamma -- metabolism
- Male
- Sarcoma, Ewing -- drug therapy
- Survival Rate
- TNF-Related Apoptosis-Inducing Ligand -- metabolism
- Up-Regulation
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Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
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