Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cells. [electronic resource]
Producer: 20071019Description: 1448-57 p. digitalISSN:- 0006-4971
- Animals
- Chromatin -- genetics
- Chromosomal Proteins, Non-Histone -- genetics
- Cytomegalovirus -- genetics
- Disease Models, Animal
- Enhancer Elements, Genetic
- Gene Expression
- Gene Silencing
- Genetic Therapy
- Genetic Vectors
- Genome, Viral -- genetics
- HeLa Cells
- Hematopoietic Stem Cells
- Heterogeneous-Nuclear Ribonucleoprotein Group A-B -- genetics
- Humans
- Interleukin-2 -- genetics
- K562 Cells
- Lentivirus -- genetics
- Mice
- Mice, SCID
- Promoter Regions, Genetic -- genetics
- Signal Transduction -- genetics
- Spleen Focus-Forming Viruses -- genetics
- Transduction, Genetic
- Transgenes -- physiology
- Virus Integration -- genetics
- X-Linked Combined Immunodeficiency Diseases -- genetics
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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