Activation of NADPH oxidase by transforming growth factor-beta in hepatocytes mediates up-regulation of epidermal growth factor receptor ligands through a nuclear factor-kappaB-dependent mechanism. [electronic resource]
Producer: 20070710Description: 251-9 p. digitalISSN:- 1470-8728
- Acetophenones -- pharmacology
- Animals
- Anthracenes -- pharmacology
- Benzamides -- pharmacology
- Chromones -- pharmacology
- Dioxoles -- pharmacology
- Enzyme Activation -- drug effects
- Epidermal Growth Factor -- metabolism
- ErbB Receptors -- metabolism
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Flavonoids -- pharmacology
- Heparin-binding EGF-like Growth Factor
- Hepatocytes -- enzymology
- Humans
- Imidazoles -- pharmacology
- Intercellular Signaling Peptides and Proteins
- Morpholines -- pharmacology
- NADH, NADPH Oxidoreductases -- biosynthesis
- NADPH Oxidase 1
- NADPH Oxidase 4
- NADPH Oxidases -- antagonists & inhibitors
- NF-kappa B -- physiology
- Onium Compounds -- pharmacology
- Peptides -- pharmacology
- Phosphatidylinositol 3-Kinases -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Quinazolines
- Rats
- Reactive Oxygen Species -- pharmacology
- Transforming Growth Factor beta -- physiology
- Tyrphostins -- pharmacology
- Up-Regulation
- rac1 GTP-Binding Protein -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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