Identification of a novel glutathione conjugate of flutamide in incubations with human liver microsomes. [electronic resource]
Producer: 20070724Description: 1081-8 p. digitalISSN:- 0090-9556
- Androgen Antagonists -- chemistry
- Antineoplastic Agents, Hormonal -- chemistry
- Aryl Hydrocarbon Hydroxylases -- metabolism
- Biotransformation
- Chemical and Drug Induced Liver Injury
- Chromatography, High Pressure Liquid
- Cytochrome P-450 CYP1A2 -- metabolism
- Cytochrome P-450 CYP2C19
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme System -- genetics
- Flutamide -- chemistry
- Glutathione -- metabolism
- Humans
- In Vitro Techniques
- Magnetic Resonance Spectroscopy
- Microsomes, Liver -- enzymology
- Mixed Function Oxygenases -- metabolism
- Molecular Structure
- NADP -- metabolism
- Recombinant Proteins -- metabolism
- Tandem Mass Spectrometry
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Publication Type: Journal Article
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