CTLA-4 expressed by chemoresistant, as well as untreated, myeloid leukaemia cells can be targeted with ligands to induce apoptosis. [electronic resource]
Producer: 20070424Description: 597-608 p. digitalISSN:- 0007-1048
- Adult
- Aged
- Antigens, CD -- genetics
- Antigens, Differentiation -- genetics
- Antigens, Neoplasm -- metabolism
- Apoptosis
- B7-1 Antigen -- metabolism
- B7-2 Antigen -- metabolism
- CTLA-4 Antigen
- Caspases -- metabolism
- Drug Resistance, Neoplasm
- Female
- Humans
- Leukemia, Myeloid -- drug therapy
- Ligands
- Male
- Middle Aged
- Reverse Transcriptase Polymerase Chain Reaction -- methods
- Transcription, Genetic
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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