Population estimation of the effects of cytochrome P450 2C9 and 2C19 polymorphisms on phenobarbital clearance in Japanese. [electronic resource]
Producer: 20070730Description: 118-21 p. digitalISSN:- 0163-4356
- Adult
- Algorithms
- Anticonvulsants -- metabolism
- Aryl Hydrocarbon Hydroxylases -- genetics
- Asian People -- genetics
- Cytochrome P-450 CYP2C19
- Cytochrome P-450 CYP2C9
- Drug Monitoring -- methods
- Epilepsy -- blood
- Female
- Gene Frequency
- Genetics, Population
- Heterozygote
- Homozygote
- Humans
- Immunoassay
- Isoxazoles -- metabolism
- Japan
- Male
- Metabolic Clearance Rate
- Mixed Function Oxygenases -- genetics
- Phenobarbital -- metabolism
- Phenytoin -- metabolism
- Polymorphism, Genetic
- Regression Analysis
- Valproic Acid -- metabolism
- Zonisamide
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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