Manipulating glutathione-S-transferases may prevent the development of tolerance to nitroglycerin. [electronic resource]
Producer: 20070307Description: 131-44 p. digitalISSN:- 1530-7905
- Animals
- Apoptosis -- drug effects
- Blotting, Western
- Cell Line
- Cyclic GMP -- physiology
- Drug Tolerance
- Endothelial Cells -- drug effects
- Glutathione Transferase -- drug effects
- Mice
- Microscopy, Confocal
- Muscle, Smooth -- cytology
- Nitric Oxide -- physiology
- Nitric Oxide Synthase Type III -- metabolism
- Nitroglycerin -- pharmacology
- Oxidative Stress -- drug effects
- Peroxynitrous Acid -- metabolism
- Signal Transduction -- drug effects
- Transfection
- Vasodilator Agents -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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