Single amino acid substitutions dissociate fibrinogen-clotting and thrombomodulin-binding activities of human thrombin. [electronic resource]
Producer: 19910904Description: 6775-9 p. digitalISSN:- 0027-8424
- Amino Acid Sequence
- Animals
- Cell Line
- Computer Simulation
- Fibrinogen -- metabolism
- Humans
- Kinetics
- Models, Molecular
- Mutagenesis, Site-Directed
- Platelet Aggregation -- drug effects
- Protein Conformation
- Prothrombin -- genetics
- Receptors, Cell Surface -- metabolism
- Receptors, Thrombin
- Recombinant Proteins -- metabolism
- Thrombin -- genetics
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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