DA-9601, a standardized extract of Artemisia asiatica, blocks TNF-alpha-induced IL-8 and CCL20 production by inhibiting p38 kinase and NF-kappaB pathways in human gastric epithelial cells. [electronic resource]
Producer: 20070410Description: 4850-8 p. digitalISSN:- 1007-9327
- Artemisia -- chemistry
- Chemokine CCL20
- Chemokines, CC -- genetics
- Enzyme Inhibitors -- metabolism
- Epithelial Cells -- cytology
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Gastric Mucosa -- cytology
- Genes, Reporter
- Humans
- Interleukin-8 -- genetics
- JNK Mitogen-Activated Protein Kinases -- metabolism
- Macrophage Inflammatory Proteins -- genetics
- NF-kappa B -- antagonists & inhibitors
- Plant Extracts -- chemistry
- Promoter Regions, Genetic
- Signal Transduction -- physiology
- Transcription, Genetic
- Tumor Necrosis Factor-alpha -- metabolism
- p38 Mitogen-Activated Protein Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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