A chromosome 8 gene-cluster polymorphism with low human beta-defensin 2 gene copy number predisposes to Crohn disease of the colon. [electronic resource]
Producer: 20061019Description: 439-48 p. digitalISSN:- 0002-9297
- Chromosomes, Human, Pair 8 -- genetics
- Colon -- metabolism
- Crohn Disease -- genetics
- DNA Mutational Analysis
- Gene Dosage
- Gene Expression
- Genetic Predisposition to Disease
- Humans
- Inflammatory Bowel Diseases -- genetics
- Multigene Family
- Oligonucleotide Array Sequence Analysis
- Polymorphism, Genetic
- beta-Defensins -- deficiency
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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