Apoptotic effect of ethyl-4-isothiocyanatobutanoate is associated with DNA damage, proteasomal activity and induction of p53 and p21cip1/waf1. [electronic resource]
Producer: 20070126Description: 1299-310 p. digitalISSN:- 1360-8185
- Amino Acid Chloromethyl Ketones -- pharmacology
- Apoptosis -- drug effects
- Ataxia Telangiectasia Mutated Proteins
- Butyrates -- administration & dosage
- Caffeine -- pharmacology
- Cell Cycle -- drug effects
- Cell Cycle Proteins -- antagonists & inhibitors
- Cell Line
- Chromosome Aberrations -- drug effects
- Cyclin-Dependent Kinase Inhibitor p21 -- biosynthesis
- DNA Damage
- Flow Cytometry
- Humans
- Isothiocyanates -- administration & dosage
- Leupeptins -- pharmacology
- Membrane Potential, Mitochondrial -- drug effects
- Proteasome Endopeptidase Complex -- metabolism
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Tumor Suppressor Protein p53 -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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