Anti-CD20 monoclonal antibody with enhanced affinity for CD16 activates NK cells at lower concentrations and more effectively than rituximab. [electronic resource]
Producer: 20061102Description: 2648-54 p. digitalISSN:- 0006-4971
- Antibodies, Monoclonal -- administration & dosage
- Antibodies, Monoclonal, Murine-Derived
- Antibody-Dependent Cell Cytotoxicity
- Antigens, CD -- genetics
- Antigens, CD20 -- immunology
- Base Sequence
- DNA -- genetics
- GPI-Linked Proteins
- Humans
- In Vitro Techniques
- Intercellular Adhesion Molecule-1 -- metabolism
- Killer Cells, Natural -- immunology
- Leukemia, Lymphocytic, Chronic, B-Cell -- immunology
- Polymorphism, Genetic
- Receptors, IgG -- genetics
- Rituximab
- Up-Regulation
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural
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