Increased level and longevity of protective immune responses induced by DNA vaccine expressing the HIV-1 Env glycoprotein when combined with IL-21 and IL-15 gene delivery. [electronic resource]
Producer: 20060809Description: 177-91 p. digitalISSN:- 0022-1767
- AIDS Vaccines -- administration & dosage
- Adjuvants, Immunologic -- administration & dosage
- Animals
- Antibody-Dependent Cell Cytotoxicity -- genetics
- CD8-Positive T-Lymphocytes -- immunology
- Combined Modality Therapy
- Female
- Gene Products, env -- administration & dosage
- Gene Transfer Techniques
- HIV Antibodies -- biosynthesis
- HIV-1 -- genetics
- Immunization, Secondary
- Interleukin-15 -- administration & dosage
- Interleukins -- administration & dosage
- Mice
- Mice, Inbred BALB C
- Mice, Transgenic
- Neutralization Tests
- Rabbits
- Vaccines, DNA -- administration & dosage
- Vaccinia virus -- genetics
- env Gene Products, Human Immunodeficiency Virus
- Interleukin-21
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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